NEW PUBLICATION: AB INITIO CHEMICAL SAFETY ASSESSMENT: A WORKFLOW BASED ON EXPOSURE CONSIDERATIONS AND NON-ANIMAL METHODS

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A workflow for chemical safety assessment is described and illustrated that completely avoids animal testing. The workflow, developed within the SEURAT-1 initiative, was designed to assess chemical safety without relying on any animal testing, constructing a hypothesis based on existing data, in silico modelling, biokinetic considerations and then by targeted non-animal testing. The general nature of the approach is applicable to cosmetic ingredients as well as to other types of chemicals, e.g. active ingredients in plant protection products, biocides or pharmaceuticals.

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