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Unilever’s Safety & Environmental Assurance Centre is an organisation that constantly seeks to bring new science to the safety and environmental impact assessment of the ingredients in Unilever products. The toxicology that underpins those assessments is rapidly evolving and this website represents the efforts Unilever and our global scientific partners are taking to progress 21st Century Safety Science

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New Publication: Flutamide-induced hepatic cell death and mitochondrial dysfunction involves inhibition of Nrf-2 mediated heme oxygenase 1 induction

Flutamide is a widely used nonsteroidal anti-androgen for prostate cancer therapy, but its clinical […]

New Presentation: Understanding biotransformation of slowly cleared chemicals in in-vitro hepatic models

Early prediction of clearance in human is often challenging, in particular for the growing […]

New Presentation: Challenges in Developing systems models for safety decision making

The development of NGRA approaches will require a combination of both in vitro experimental […]

New Publication: High-throughput analysis using non-depletive SPME: challenges and applications to the determination of free and total concentrations in small sample volumes

In vitro high-throughput non-depletive and non destructive determination of concentrations of chemicals in biological […]

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